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Concurrently, vitamin B12 deficiency was identified as a significant public health concern, particularly among vulnerable populations such as the elderly and developing embryos, where insufficient B12 levels have been associated with an increased risk of neural tube defects

In addition, the experimental halo effect in copper maps may indicate co-localization of copper with a ring rich in lipids, observed around the A plaque in AD models [278] and human AD sections [279]

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