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There was also no long-term follow-up to assess if any delayed complications (for example, abnormal tissue growth or tumor formation) occurred after the injection

In the absence of implantation , diminishing LH and FSH levels result in corpus luteum breakdown, decreased production of progesterone and estrogen, sloughing away of the endometrium through menstruation, and the start of a new cycle

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In vitro experiments on lung cancer cells revealed that L-asparaginase treatment significantly induced autophagy activation in A549 cells, leading to their apoptosis (108)