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Free radicals or reactive species through oxidative stress have been evidently implicated in the incidence and progression of several health conditions such as atherosclerosis, diabetes, cancer, neurodegenerative disorders, cardiovascular disorders and other chronic conditions.1 Oxidative stress is a cellular phenomenon or condition which occurs as a result of physiological imbalance between the levels of antioxidants and oxidants (free radicals or reactive species) in favour of oxidants (Fig

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Investigating VPA toxicokinetics and concentration/effect relationships may help understanding how to improve VPA-poisoned patient management