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These studies confirmed the weight lowering efficacy of liraglutide in this setting, showing a BW change ranging from 6.0% to 5.8% with liraglutide compared to 2.0 to 1.5% with placebo 21,22

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33 More recently it has been demonstrated that EphA4, a member of the Eph family of receptor tyrosine kinases, may interact with the GHR