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In that time, youth smoking rates have plummeted, suggesting that the increase has kept tobacco products out of schools and preserved young lungs

This former observation was likely due to the trend poorer hit rate in HIV+/Smok- relative to HIV-/Smok- participants ( p = 0.06), indicating the impact of HIV on target detections amongst non-smokers

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In this review we discuss the pathophysiologic mechanisms of PAD, with focus on differences in thrombo-inflammatory processes between diabetes-related and smoking-related PAD, and hypothesize on possible mechanisms for the progressive course of PAD in DM