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Prolonged inhalation of diacetyl caused several workers to develop severe, irreversible lung damage - hence, the nickname "popcorn lung." Causes of Popcorn Lung While rare, popcorn lung can be caused by various inhaled toxins or injuries, including: Diacetyl (found in some flavored e-cigarette or vape products) Chemical fumes (e.g., industrial cleaners, flavorings, ammonia) Respiratory infections (e.g., after severe viral infections) Complications from lung or stem cell transplants Symptoms of Popcorn Lung Popcorn lung symptoms often resemble other chronic lung diseases like asthma or COPD, which can lead to misdiagnosis

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