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Regulation of desnutrin/ATGL mRNA by glucocorticoids may explain this, since dexamethasone was found to strongly upregulate the enzyme in a concentration- and dose-dependent manner in 3T3-L1 preadipocytes (130)
Oral eingenommenes BPC-157 dagegen zeigte in einer Phase-I-Untersuchung an gesunden Probanden keine messbaren Plasmaspiegel in keiner der getesteten Dosierungen (1, 3, 6 oder 9 mg/Tag) war das Peptid im Blut oder Urin nachweisbar (Sikiric et al., Pharmaceuticals 2025)
