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Possible reasons include the Washington State University patent holders not finding a pharmaceutical company willing to invest in development, the cancer biology concern with c-Met activation making development companies cautious, the preclinical effect sizes in rats not justifying the expense and risk of human trials, or other factors specific to drug development economics

By injecting B12 directly into the bloodstream, we can quickly and efficiently restore healthy levels, helping to boost energy, improve concentration, and enhance overall well-being for our patients

Bachem, Switzerland) were infused for 1020 min at 3.5 or 12 mmol/l glucose separated by 20 min rest periods to allow secretion to return to basal level