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It also has a role in wound healing

Therefore, although current data support Nrf2 as an important regulatory point upstream of GPX4, its precise mode of action at various stages of OA progression and the long-term safety of pharmacological activation require further systematic investigation

Caregivers should avoid self-prescribing high doses of vitamins or minerals, as excessive intake can lead to toxicity or nutrient imbalances

Increased lactate concentrations are also intriguing in the context of one of the influential hypotheses on the provenience of ME/CFS symptoms, a state of chronic, low-level neuroinflammation [61]