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Why Addressing the Nervous System Is Essential If the nervous system is not addressed, pain may: Spread beyond the original injury site Return quickly after medications wear off Worsen during stress or fatigue Become resistant to escalating interventions This helps explain why chronic pain frequently persists despite normal imaging, laboratory results, or repeated structural treatments

ACKNOWLEDGEMENTS The authors would like to thank individuals who contributed their part to the successful development of this article

Many individuals taking tirzepatide for weight management may simultaneously use creatine to preserve or build lean muscle mass during caloric restrictiona reasonable approach given that GLP-1 receptor agonists can lead to loss of both fat and muscle tissue