Gan R-Y, Chan C-L, Yang Q-Q, Li H-B, Zhang D, Ge Y-Y, et al
It also has a certain effect on autoimmune diseases such as RA, bronchial asthma, multiple sclerosis and systemic lupus erythematosus ( Apigenin Apigenin is a dietary flavonoid compound widely distributed in fruits and vegetables, and has multiple biological activities such as anti-inflammation, anti-oxidation, and pro-apoptosis ( In vitro , apigenin inhibits LPS-stimulated maturation and chemotaxis of bone marrow-derived dendritic cells (BMDC) by inhibiting the expression of costimulatory molecules (CXCR4 and CCR7) and MHCII and reducing the secretion of cytokines (TNF-a, IL-12p70 and IL-10)
Laser therapy has proven to be quite efficient in treating melasma, and some topical or oral treatments can also help reduce its intensity
Estrogen receptor beta (ER) mediates expression of -catenin and proliferation in prostate cancer cell line PC-3