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South and Central American cultures have used it for centuries to treat ailments like: Stomach problems Arthritis Inflammation Fevers While popular conceptions of the herb suggest that it might have anti-inflammatory and antioxidant properties, the research is still mixed.47 Still, cats claw is a common herbal ingredient in supplements for arthritis symptoms, and one study found it improved cognition, learning, and memory in middle-aged rats.48 The most effective dose for rats in the study was 30mg/kg, which would be about 365mg for a 150lb human, which is actually very close to the 350mg included in Alpha BRAIN