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2.3 Mechanisms linking gut microbiota dysbiosis to hypothyroidism development Gut microbiota dysbiosis exerts significant impacts on multiple physiological systems, directly and indirectly exacerbating the pathogenesis of hypothyroidism through several interconnected mechanisms

Using macrophages from healthy people and macrophages with VLCAD, the researchers showed that VLCAD induces alternative macrophage activation in response to certain pathogenic signals