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10.1016/s1499-3872(11)60085-4 106 WangW.GuanC.SunX.ZhaoZ.LiJ.FuX.et al (2016)

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In many pathological processes in which OS has an essential role, increased XO activity is involved: type 1 diabetes mellitus, in which the production of mitochondrial superoxide is not modified, and the generation of ROS thus becomes XO-dependent [29], myocardial ischemia and reperfusion lesions [30], atherosclerosis [25], and neoplastic processes [31]

Phosphotransferase activity assays The protocol for measuring the GlcNAc-phosphotransferase activity was adapted from van Meel et al