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Mucoadhesive agents have been described, for example, in U.S

Grivennikov SI, Greten FR, Karin M

The arthritis response to adalimumab in this trial was lower than has been seen with other trials of TNF inhibitors in PsA, although the ACR20 response rate improved to 65% with an additional 12 weeks of open-label therapy

However, its critical to recognize that these peptides are not FDA-approved and should only be considered in the context of education, research, and careful physician supervision