Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB
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Commercial development was discontinued in 2007 after the Phase IIb trial failed to meet its primary endpoint
This small molecule, with its unique molecular structure, has been linked to potential interactions with amino acids and as a potent activator of sirtuins, a class of proteins involved in regulating cellular health and longevity, suggesting a nuanced role in cellular processes that may further contribute to the compounds anti-aging properties