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Potential interactions include: Metformin (used for type 2 diabetes) Proton pump inhibitors (PPIs) and H2-receptor antagonists (used for acid reflux) Colchicine (used for gout) Nitrous oxide (anaesthetic gas that can inactivate B12) Chloramphenicol (may reduce the haematological response to B12 therapy) If you take any of these medications long-term, discuss B12 monitoring with your healthcare provider

The growth-promoting and angiogenic properties of the compound make its use in pregnancy particularly concerning: aberrant angiogenesis during placental development is associated with preeclampsia and fetal growth disorders

[DOI] [PubMed] [Google Scholar] 121.Lovric-Bencic M., Sikiric P., Hanzevacki J.S., Seiwerth S., Rogic D., Kusec V., Aralica G., Konjevoda P., Batelja L., Blagaic A.B

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