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Remethylation requires folate and B12 coenzymes while transsulfuration requires pyridoxal-5-phosphate, the B6 coenzyme

After an injury, the body releases TB4, which works to reduce inflammation and protect cells and tissues from further damage. The authors go on to explain that TB4s tissue regeneration ability is partially due to its promoting the formation of new blood vessels (angiogenesis)

Neurological: Numbness or tingling in the extremities (paresthesias), difficulty walking, balance problems, muscle weakness, vision problems, cognitive disorders (difficulty concentrating, memory loss), mood changes (depression, irritability)

Another rare side effect