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A condition of low-grade inflammation has been related to NAFLD, with an abnormal production of cytokines and adipokines, such as interleukin (IL)-6, tumor necrosis factor (TNF)-, IL-1, leptin

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Research has shown that UA can facilitate the formation of mitochondrial respiratory chain complexes and enhance their function, increasing ATP synthesis in muscle cells (6)

Keller was a faculty member of the Mayo Graduate School of Medicine, the University of Wisconsin and the Medical College of Wisconsin (Marquette Univ.) He published more than 100 original articles in various scientific and medical journals and has been awarded several patents