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97 In addition, buforin II B, an AMP derived from histone H2A, can pass through the tumor cell membrane without damage, act on mitochondria, release cytochrome c, and activate the apoptosis protein caspase-9, and induce tumor cell apoptosis in the mitochondrial pathway

Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat