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Certain probiotic strains produce antimicrobial compounds that can help address bacterial overgrowth, though probiotic use in SIBO remains somewhat controversial and requires careful strain selection

Smoking and pollution exposure: Smoking and air pollution increase free radical production

After reconstitution: refrigerate the mixed vial and use bacteriostatic (not sterile) water so the multi-dose vial resists microbial growth across ~30 draws

Rett syndrome, caused by MECP2 gene mutations, disrupts GABAergic interneuron development, lowering GABA concentrations in the hippocampus and prefrontal cortex, leading to developmental regression, such as loss of language and motor skills, and stereotypic hand movements like hand-wringing (77)