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E-cigarettes may be safer than regular cigarettes for adults who are transitioning from smoking to vaping, but for youth who have never used any other tobacco products, nicotine experimentation could become nicotine addiction. The study was supported by the National Institutes of Health National Cancer Institute and the Food and Drug Administration Center for Tobacco Products (P50CA180905)

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If the desired therapeutic effect is not obtained, the treatment should be interrupted and another cycle could be attempted after 23 months

Use of flavored e-cigarettes among adolescents, young adults, and older adults: findings from the population assessment for tobacco and health study