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Other amino acids present include serine, -alanine, glutamic acid, histidine, and glycine ( Manuka honeys MGO interfere with bacterial protein synthesis and may serve as a signaling molecule in plants, though intracellular accumulation in high concentrations can cause apoptosis ( In vivo experiments demonstrate radioprotective properties, as honey-treated fibroblasts maintained metabolic function following irradiation ( 4 Mechanistic insights into anti-cancer effects of honey 4.1 Antiproliferative and cytotoxic mechanisms Honey has several biological activities that contribute to its anticancer properties, namely four integrative mechanisms: pro-apoptosis, cell cycle arrest, regulation of inflammatory signaling pathways, and antioxidant activity

doi: 10.1172/jci.insight.158193 525 SpolskiRLeonardWJ

doi: 10.1016/0168-8227(94)90155-4 14 van DijkPRLogtenbergSJChisalitaSIHedmanCAGroenierKHGansROet al

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