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Nrf2 signaling contributes to the neuroprotective effects of urate against 6-OHDA toxicity

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The IgG variants were purified using CaptureSelect C H 1 columns (Thermo Fisher) prior to size exclusion chromatography (SEC) to isolate monomeric fractions using a Superdex 200 Increase 10/300 column (Cytiva Life Sciences) with an KTA Avant 25 (Cytiva Life Sciences)