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The major ferroptosis-related pathways influenced by polysaccharides are the SLC7A11/GSH/GPX4 pathway, Keap1/Nrf2/HO-1 pathway, NCOA4-mediated ferritinophagy pathway, ACSL4-mediated lipid peroxidation pathway, and their upstream signal such as PI3K/Akt, Wnt/-catenin, p53, and the AMPK/BECN1 autophagy pathway

The peptide is supplied exclusively for: Scientific research Laboratory investigation Experimental aging studies Human safety data remains extremely limited, and additional long-term research is required

Peptide therapy can help address the root cause of this imbalance

Cells were transiently transfected with 0100 n M siRNA complex using Lipofectamine2000 transfection reagent (Invitrogen, Carlsbad, CA) following the method described earlier (26, 43)