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MMP-9 MMP-9 plasma concentration is a strong marker of BBB disruption and permeability in stroke

This process is exacerbated by smoking, pollution, exposure to UV or ionizing radiation, eating fried foods or those cooked at high temperatures, as well as engaging in high-intensity exercise (12)

In an Egyptian study [19], the authors found significant differences between the double present genotype (+/+) and either or both null genotypes of diabetics (P = 0.002 and P = 0.009 respectively) when compared to the control subjects