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The estimated oral dose range from animal research is approximately 18 mg/kg, but human pharmacokinetic parameters including bioavailability fraction, Tmax, and clearance remain entirely unknown

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Human whole blood aliquots were spiked with various concentrations of ipamorelin acquired from Millipore Sigma (Saint Louis, MO)

doi: 10.3389/fonc.2025.1673513 Received 26 July 2025 Accepted 02 October 2025 Published 16 October 2025 Volume 15 - 2025 Edited by Rafael Moreno-Snchez, National Autonomous University of Mexico, Mexico Reviewed by Sara Rodriguez-Enriquez, Facultad de Estudios Superiores Iztacala, Mexico Gio Fidelito, University of Melbourne, Australia Farida Usman, Bayero University Faculty of Basic Medical Sciences, Nigeria Updates Copyright 2025 Ye, Wu, Li, Ye, Rao, Liu and Gao