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Brain metabolism along with sleep impairment play a crucial role in deteriorating cellular and system homeostasis that contributes to cognitive decline as well as aging trajectories (Gonzales et al., 2022

TGR inhibition in worms: TRFS-Green fluorescence quantification and GSH/GSSG determination TGR inhibition in NTS was assessed using a fluorescent probe TRFS-Green (Medchemexpress) 43

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[20] Many peptide-based compounds are supplied in lyophilised (freeze-dried) powder form because the peptide structure is more stable when dry and has a longer shelf life