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However, an excess of pro-angiogenic factors such as VEGF can trigger the production of pro-inflammatory cytokines and neuroinflammation, potentially contributing to neurodegeneration (McConnell et al

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Prevalence of clinical Alzheimer's dementia and other dementias in the United States An estimated 7.4 million Americans age 65 and older are living with clinical Alzheimer's dementia in 2026.A2 , 276 Seventyfour percent are age 75 or older (Figure 4)