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Studies have demonstrated that salidroside significantly reduces airway inflammation and oxidative stress in asthmatic models by decreasing the levels of pro-inflammatory cytokines such as IL4, IL5, and IL13, while increasing the levels of anti-inflammatory cytokines, such as IFN and IL10, in bronchoalveolar lavage fluid [226]

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However, the nonenzymatic formation of roGFP(S 2 ) from roGFP2(SSG) also proceeds extremely rapidly and competes with the final enzyme-catalyzed reaction step with implications for redox measurements as outlined below

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