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For example, MarR is glutathionylated under oxidative conditions, 89 suggesting that other thiol-containing proteins, potentially including antibiotic targets or regulators, may also be modified in vivo

In addition, patients with gastroesophageal reflux can also have esophageal mucosal eosinophilia that responds to vigorous acid blockade

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Therapeutic peptides work on that same principle: you're not introducing a foreign substance (when manufactured safely), you're speaking the body's own language, just at a higher volume and for longer than it would naturally sustain