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The ascending color gradient from green to red illustrates the progressive increase in clinical severity with higher tyramine doses

Potential Benefits of a Combined Approach (Under Medical Guidance) When managed by a healthcare professional, a combined approach of B12 injections and tablets might offer several advantages for specific individuals: Potentially Less Frequent Injections: For those who find injections inconvenient or uncomfortable, a combined regimen could mean fewer trips to the clinic for jabs, improving quality of life

Kryger M, Wang-Weigand S, Roth T

When using methylated SDC2-A alone, the sensitivity was 85.29%, and when using methylated SDC2-B alone, the sensitivity was 83.33% (Ma et al., 2022a)