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Campaigners have said the 50c increase on the excise duty on a packet of 20 cigarettes is "unfair" on law-abiding consumers and retailers in Ireland

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Many studies have also shown that human and mouse cells also have ample supplies of cytochrome p450, which further converts NNN and NNK into compounds such as formaldehyde and methyldiazohydroxide that can react with DNA to form damaging adducts such as gamma-hydroxy-propanodeoxyguanosine and O6-methyl-deoxyguanosine, the researchers say