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Erlotinib OMNI379 Itraconazole (R51211) is a triazole

SKU: 49544117128

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Description

Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM

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Erlotinib OMNI379 Itraconazole (R51211) is a triazoleErlotinib (CP 358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non small cell lung cancer. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper catalyzed azide alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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