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These findings directly implicate mtNOS hyperactivity in driving mitochondrial problems in CRC (129)

After stirring at room temperature over 48 h, the mixture was neutralized with saturated aqueous NaHCO 3 solution and partitioned between ethyl acetate and water

Furthermore, Gln metabolism contributes to chemotherapy resistance in prostate cancer cells by modulating drug efflux, particularly through the upregulation of the ATP-binding cassette transporter ABCB1 (224)

It means the therapy may be worth discussing when symptoms suggest that local airway support could help, and when the patient is stable enough to tolerate inhaled treatment