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van Ommen B, den Besten C, Rutten AL, Ploemen JH, Vos RM, Muller F, van Bladeren PJ: Active site-directed irreversible inhibition of glutathione S-transferases by the glutathione conjugate of tetrachloro-1,4-benzoquinone

Generally, glutathione is considered safe for most adults when used as a nutritional supplement