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Different types of acne are treated, including pimples on face, whiteheads, blackheads, papules, pustules, nodules, cysts

In milder or borderline cases, high-dose oral vitamin B12 may be sufficient, depending on absorption and clinical context

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The complex crystallized under sitting drop vapour diffusion against 24% PEG 3350 and 100 mM MES (pH 6.5) with a drop configuration of 2 l of complex, 1.8 l well and 0.2 l 40% tert-butanol