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Proline residues introduce rigid kinks into peptide chains, conferring conformational rigidity that resists enzymatic cleavage

For example, in a controlled feeding study in healthy young men, 37% of heme iron was bioavailable compared to only 5% of non-heme iron (Bjorn-Rasmussen 1974)

GHK-Cu modulates both MMP activity and their inhibitors, essentially overseeing a tissue remodeling process rather than just adding more material

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