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Reduced BDNF levels correlate with amyloid-beta accumulation, tau pathology, and neuronal loss in the hippocampus and cortex

Epithelial MLCK-dependent barrier dysfunction mediates T-cell activation-induced diarrhea in vivo Cytoskeletal contraction due to myosin II (regulatory)-light chain (MLC) phosphorylation is necessary for barrier disruption and in vitro inhibition of myosin light chain kinase (MLCK) restores barrier function following cytokine treatment

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