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Your nicotine receptors desensitize within seconds of exposure , and your brain compensates by producing more binding sites , a process called upregulation

PMID 27711031

You might be surprised to know some of the chemicals in tobacco smoke include: Arsenic used in pesticides Benzene important component in gasoline Formaldehyde used for embalming human remains and in nail polishes/hardeners Methanol a simple alcohol used in antifreeze, solvents and fuels Ammonia used in many commercial cleaning products How nicotine affects your brain The physical challenge of smoking is difficult because tobacco contains an addicting drug called nicotine

Gallus claims that the users of heated tobacco products in Italy tend to be young, pointing to surveys which have described their use as widespread among adolescents