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The DSM-5 does not classify any substance as a gateway drug. The DSM-5 recognizes 10 substance classes and diagnoses substance use disorder across mild (2 to 3 criteria), moderate (4 to 5 criteria), and severe (6 or more criteria) severity levels based on 11 standardized criteria, with no reference to sequential initiation patterns

Take a look at a new study that supports this view

The summit of this mountain was breathtaking, and now over, it was time to descend into another valley of uncertainty

Tests for cotinine can be either qualitative (a simple positive/negative result) or quantitative (measuring the exact concentration)