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Verdict at a Glance CagriSema and tirzepatide achieve remarkably similar weight loss (20.4% vs 20.9%) through fundamentally different dual mechanisms -- amylin/GLP-1 versus GIP/GLP-1

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We explained that this important result arises from the very slow change of GSH as LIMITATIONS Our models are based on the underlying physiology and the kinetics of the enzymes, but no model can encompass the entirety of biological complexity

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