The regulatory effect of NRF2 on those genes was well documented through antioxidative response element binding in the promoter or enhancers of target genes
Water/Aqua/Eau, Tetrahexyldecyl Ascorbate (vitamin C/antioxidant), Dimethicone (silicone/emollient), Glycerin (humectant), C912 Alkane (solvent), Ascorbyl Glucoside (vitamin C/antioxidant), Silica (texture enhancer), Pyrus Malus (Apple) Fruit Extract (plant extracts/antioxidant), Hydrogenated Lecithin (emollient), Polyglyceryl6 Polyricinoleate (emulsifier/suspending/dispersing agent), Acrylates/C1030 Alkyl Acrylate Crosspolymer (texture enhancer), Xanthan Gum (texture enhancer), Glutathione (antioxidant), Ergothioneine (antioxidant), Oryza Sativa (Rice) Bran Extract (plant extracts/antioxidant), Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer (suspending/dispersing agent), Cetyl Alcohol (emollient), Caprylyl Glycol (humectant), Lysine Carboxymethyl Cysteinate (antioxidant), CocoCaprylate/Caprate (emollient), Tocopherol (vitamin E/antioxidant), Sodium Citrate (pH adjuster), Sodium Phytate (chelating agent), Hexylene Glycol (humectant), Ethylhexylglycerin (humectant), Helianthus Annuus (Sunflower) Extract (plant extracts/antioxidant), Urea (humectant), Mannitol (humectant), Caprylic/Capric Triglyceride (emollient), Sodium PCA (humectant), Rosmarinus Officinalis (Rosemary) Leaf Extract (plant extracts/antioxidant), Polysorbate 60 (emulsifier), Sorbitan Isostearate (emulsifier), Trehalose (humectant), Ascorbic Acid (vitamin C/antioxidant), Glucose (humectant), Vanilla Planifolia Fruit Extract (plant extracts/antioxidant), Polyquaternium51 (filmforming agent), Triacetin (solvent), Sodium Hyaluronate (humectant), Phenoxyethanol (preservative)
This formulation utilizes three ways to support glutathione: intracellular with SAG, intracellular biosynthesis with NAC, and extra/intracellular (systemic) support with GSH
These include oral tablets that work best on an empty stomach, intravenous infusions lasting 15-20 minutes, topical applications, and inhalants
