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Abstract This study employed a comprehensive proteomic and metabolomic analysis to characterize adaptive cellular mechanisms of priority pathogens Escherichia coli, Klebsiella pneumoniae, Enterococcus faecium , and Staphylococcus aureus under sub-inhibitory concentrations of antibiotics

FOXO4-DRI (Proxofim) is a D-retro-inverso senolytic peptide that selectively clears senescent "zombie" cells by disrupting the FOXO4-p53 survival interaction

In a landmark double-blind, placebo-controlled crossover study of 20 men with psychogenic and organic erectile dysfunction, Melanotan II induced penile erections in 17 of 20 subjects (85%) in the absence of sexual stimulation

Nuclear factor erythroid 2-related factor 2 (NRF2) and its repressor, KEAP1, have been demonstrated to exert regulatory functions in serine/glycine metabolism