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The diversity of tumor types and the complex nature of brain tissue responses to radiation underscore the limitations of a universal treatment approach

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The ZIP family enables Zn to enter the cytosol, the HMA family aids in Zn efflux to the apoplast, and the MTP family aids in Zn sequestration in cellular compartments such as the vacuole

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Experimentally this is measured by comparing the Area-Under-the-Curve (AUC) of the drug when serial measurements of plasma concentration are made following oral administration compared to i.v

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58 As an APC, especially myeloid DCs have been shown to induce T cell differentiation

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