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This significant discrepancy between physiological requirements and therapeutic doses highlights the need for a deeper understanding of B12 absorption dynamics, rather than focusing solely on intake quantity

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J Pharmacol Exp Ther 255:13771384 Beiu AM, Noveanu L, Hncu IM, Lascu A, Petrescu L, Maack C, Elmr E, Muntean DM (2022) Mitochondrial effects of common cardiovascular medications: the good, the bad and the mixed