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Pets may serve as effective sentinels of environmental risk, not only due to their close contact with human environments but also because of their demonstrated physiological responses to tobacco smoke

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The study Vapors Produced by Electronic Cigarettes and E-Juices with Flavorings Induce Toxicity, Oxidative Stress, and Inflammatory Response in Lung Epithelial Cells and in Mouse Lung found: There are approximately 10 15 free radicals in a puff of conventional cigarette smoke in addition to heavy metals nanoparticles which have also recently been shown in e-cig aerosols to similar levels per puff [10,16]