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No noticeable effect: in research terms, FOXO4-DRI only acts where senescent cells are present, and degraded or mislabeled product loses activity

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doi: 10.3390/app13031571 205

Treatment with febuxostat did not reduce significantly the progression renal disease, with a fall in eGFR in the placebo group of (-0.47 4.48 ml/min/1.73 m2) vs 0.23 5.26 ml/min/1.73 m2 in the febuxostat group