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Oral B12 is most effective for people who: Follow a diet that includes plants Experience mild symptoms Need daily support to stay healthy Like taking supplements at home Do not have absorption problems The American Academy of Family Physicians explains that taking B12 works well to treat mild issues and for general supplementation, provided there are no absorption problems

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The role of metformin on vitamin B12 deficiency: a meta-analysis review

1 2 Proceedings of the National Academy of Sciences of the United States of America