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Although analgesics such as NSAIDs are widely used for pain control, they cause some adverse reactions such as upper gastrointestinal bleeding [1, 2, 3]

This ensures maximum absorption and utilization by the body, bypassing the digestive system, where oral supplements may be less effective

doi: 10.3389/fendo.2024.1484838 Received 22 August 2024 Accepted 29 October 2024 Published 14 November 2024 Volume 15 - 2024 Edited by Chao Cheng, Wuxi Peoples Hospital of Nanjing Medical University, China Reviewed by Aimin Jiang, Fudan University, China Jiaheng Xie, Central South University, China Updates Copyright 2024 Hu, Tian, Deng, Wang, Li, Wang, Liu and Li

Addressing these gaps will require integrated multi-omics and subcellular-resolution studies to establish a more precise and context-dependent regulatory framework for ferroptosis